Woman On Sertraline for Two Months Who Says It Has Done Nothing — Free SCA Practice Case
Woman on sertraline for two months who says it has done nothing
Station Timer
Golden Minute
Initial Introduction
•Introduce yourself
•Ask an open question — "How can I help you today?"
•Listen — don't interrupt
•Catch early cues
Data Gathering
History, ICE & Diagnosis
Clinical Management
Diagnosis, Plan & Decisions
Safety Net
Follow-up & Close
Five cases are free: a live 12-minute consultation with an AI patient each, marked, and no card.
Materials for Candidate
Please review before starting the consultation
Full Name
Bronagh Teague
Age
38 years
Consultation Type
VideoAge
38
Situation
Video Consultation. Seeing a different GP from the locum.
Reason for Encounter
"Sertraline hasn't done a thing in two months. I'd like to stop it today."
Medical Records
- ●PMH: Depression diagnosed 8 weeks ago. Postnatal depression 9 years ago, telephone CBT.
- ●Medications: Sertraline 50 mg each morning since 8 weeks ago. 28 tablets issued 8 weeks ago and 4 weeks ago.
- ●Allergies: NKDA.
- ●Social: Dental nurse. Daughter 9.
Recent Notes
- ●Locum GP, 8 weeks ago: PHQ 9 score 17. Advised to self refer to NHS Talking Therapies. Two week review not attended.
- ●Bloods: TSH, haemoglobin, ferritin normal.
Patient Script
For the friend playing the patient role
Character Overview: You are Bronagh Teague, a 38 year old dental nurse at a busy NHS practice. Your phone stays in a locker while you are in surgery. You live in a rented flat. Fourteen months ago you separated from Scott, your daughter Tilly's dad, after twelve years together. Tilly, who is 9, spends alternate weeks with each of you, swapping on Fridays after school. Six months ago Scott told you he had a new partner, Roz, and your mood dropped. Eight weeks ago a locum started you on sertraline and you have taken it, you would say, most days. Tilly is at Scott's this week. You have not taken a tablet for three days and woke this morning dizzy, sick and tearful, which is why you booked today. You have decided the tablets are not for you. You are quick, practical and a bit dry, but your voice goes flat when you talk about how you really feel. You are not hostile and will go along with a plan that makes sense to you.
Opening Sentence: "Hi doctor. I've been on sertraline for about two months now and honestly it hasn't done a thing. I feel exactly the same as I did before, so I'd like to stop taking it, today if that's all right."
History if Asked (Data Gathering Phase)
- ●How she is now: "Flat, mostly. No better than when I started. I get through work because I put a face on, then I go home and just sit." She has lost interest in things she loved, like doing Tilly's hair in daft plaits and cooking a big Sunday dinner. Sleep: "I get off a bit easier, maybe, but I wake in the early hours and don't go back." She is wiped out, skips breakfast without losing real weight, and last week forgot to book a patient's recall. Guilt: "When Tilly's home I feel I'm putting on a show, and when she's not I feel a rubbish mum for being relieved."
- ●If asked to score her last two weeks (for example with a questionnaire): Little interest or pleasure, more than half the days. Down or hopeless, nearly every day. Sleep, more than half the days. Tired, nearly every day. Appetite, several days. Feeling a failure, more than half the days. Concentration, more than half the days. Slowed or restless, several days. Thoughts of being better off dead or of hurting herself, not at all. Total 16, "very difficult". Compared with the start: "I think it was the high teens. About the same."
- ●How she takes the tablet: "Most days, in the morning with my tea." If asked what "most days" means: "The weeks Tilly's with me, every day, because the box lives next to the kettle. The weeks she's at Scott's I miss about half. I grab a coffee on the way in and the box stays in the cupboard. Weekends are worse, because I lie in." Last tablet: "Sunday. I thought, what's the point." About two weeks of tablets left; she has not ordered more.
- ●After a missed tablet (if asked about side effects or how she feels on skipped days): "Horrible. The day after I skip I get dizzy, sick, and a fizzy buzzing in my head, like little electric zaps, when I turn my head quickly. I'm snappy and I cry at nothing. It eases a few hours after I take one, but I always assumed that was just my body not liking the tablet." She woke like that this morning. On days she takes it she notices nothing, apart from a queasy, loose tummy in the first fortnight that went.
- ●The two week check: "It was a busy day and I never rebooked it. Nobody chased it."
- ●Talking therapy (if asked): "I put my name down online. Someone rang twice while I was in surgery, then a letter said they'd closed it. I thought that was that." After Tilly was born she had about eight weeks of CBT over the phone. "It did help, actually. I didn't take anything then."
Ideas, Concerns, Expectations
Gating note: Bronagh does not raise any of this herself. Each part comes out only when the doctor asks what she thinks is going on, what worries her, what she expected from the tablets, or what she hopes for today.
- ●Ideas: She thought antidepressants worked like antibiotics, so she would be better within a couple of weeks. After two months she has decided she is one of the people they do not work for, and that the dizzy, sick, fizzing days are the tablet harming her. "I think my body's rejecting it."
- ●Concerns: Her real fear is ending up like her mother. Janice has taken antidepressants since Bronagh was a teenager, tried twice to come off and ended up in bed, and says she will never be rid of them. "I don't want to wake up at sixty and still be taking them." Only if asked what worries her about the tablets themselves: "I hate that I feel poisoned some days. How do I know it isn't doing me harm?"
- ●Expectations: She came to stop today and hopes the doctor will say that is fine. If not: "Then I want to know what the plan is, because I can't carry on feeling like this."
If Asked: Medical History and Medications
Gating note: Bronagh answers each of these plainly when the doctor asks about it.
- ●Earlier low mood: Once, after Tilly, nine years ago. This episode crept in about six months ago, after Scott told her about Roz. No highs, overspending or times of not needing sleep. No hearing or seeing things.
- ●Health and medicines: No other health problems or thyroid problem. Only the sertraline, plus ibuprofen once in a blue moon. No supplements or allergies. No contraception ("I'm not seeing anyone and I wouldn't want another baby").
- ●Family history: Her mum has been on tablets for low mood since Bronagh was a teenager.
- ●Alcohol, drugs and caffeine: A glass of wine most Saturdays, and in the weeks Tilly is away a glass on three or four nights, never more than two. No drugs. Three or four coffees a day. Does not smoke.
Social History and Lifestyle Impact
- ●Work and home: Dental nurse, eight till half past five, phone in the locker. Scott lives ten minutes away with Roz. "The weeks she's with me I'm fine in the mornings because I have to be. The weeks she's away the flat is so quiet I can't get going."
- ●Support: Her mum helps with Tilly; Bronagh does not tell her how bad it is. Karina on reception is a friend. She stopped her Thursday night Zumba class six months ago and the girls there have drifted.
- ●An empty week: "I wake in the early hours, doze, stay in bed too long, go to work, come home and sit with the telly on. I don't cook."
If Asked: Associated Symptoms
Gating note: Bronagh answers these only when the doctor asks directly.
- ●Thoughts of harming herself or ending her life: "No. Never, not even on the worst days. I just want to hide under the duvet. I couldn't do that to Tilly." Never harmed herself, no plans. What keeps her going: "Tilly, mostly. And my mum. And the girls at work, who would notice if I stopped turning up."
- ●Negatives: Not agitated or wired ("a bit twitchy when I've skipped a few"). No panic attacks, racing heart, bleeding, bruising or black stools.
Responses to Management (The Negotiation Phase)
- ●If the doctor explains that the dizzy, sick, fizzing days follow the missed tablets, including today:
- ●Reaction: Surprised, then thoughtful. "So the horrible days are from skipping them? I thought the tablet was making me ill. That actually makes sense." Asked to restart tonight: "But I feel sick already." She agrees if told it should settle within days.
- ●If the doctor says she can stop straight away, or must stay on them:
- ●Reaction: Told she can stop: relieved, then unsure. "So I just bin the rest? Will I get the dizzy thing every day then?" Told she must stay on: defensive. "It's my body. I've done what I was told for two months and I feel the same." A slow stop: "Is that a month of feeling rubbish?"
- ●If the doctor suggests carrying on at 50 mg every day, a higher dose, or a different tablet:
- ●Reaction: Carrying on: doubtful, "What's different?" She accepts when told two months were not a fair test. A higher dose: alarmed, "If I feel sick on one, surely two is worse." She accepts if told most of her trouble came from the missed days and the dose can come back down. A different tablet: cautious, "Will I get all the sick feelings again?" She is open to it if told what to expect.
- ●If the doctor explains how long treatment lasts, or asks about her mother:
- ●Reaction: Dismayed at "six months after I feel better": "That's what my mum says. I told you I don't want to be on them forever." She calms if told it is reviewed, has an end point and is stopped slowly. About her mother: "I worry that's me in twenty years." A flat "don't worry, that won't happen" leaves her quiet: "Easy for you to say."
- ●If the doctor suggests talking therapy again, or something for the weeks Tilly is away:
- ●Reaction: Practical. "It helped after Tilly. But the last lot only ring in the day. Could they text me, or do video in the evening? On the weeks Tilly's away I'm free after six." For the quiet weeks: "Maybe I could go back to my Thursday class. Karina's been on at me. Or go round to Mum's on Sundays."
- ●If the doctor gives safety netting, offers a review, or asks her to check her own pulse or blood pressure:
- ●Reaction: Vague netting such as "come back if you feel worse": "Worse how? What would mean I ought to ring you today?" A review: "Two weeks is fine. Can it be a video call, and can you text me?" Self checks: "I haven't got a machine. I can come in."
Mark Scheme
Domain 1: Data Gathering and Diagnosis
Domain 2: Clinical Management and Medical Complexity
Domain 3: Relating to Others
Clinical Learning Points
The Core Dilemma and the Model Plan
- ●Bronagh wants to stop sertraline after eight weeks because "it hasn't done a thing". Her PHQ 9 is about 16 against 17 at the start, so the tablet has not helped yet, but she misses about half her doses in the weeks her daughter is away and has had none for three days. The skill is to judge a patchy trial fairly, explain her bad days as missed dose effects, and negotiate a safe plan rather than agree or refuse.
- ●Model answer: conclude that this has not been a fair trial, explain the missed dose effects, restart sertraline at 50 mg every morning, and increase to 100 mg once she has had at least a week of regular dosing if she tolerates it and is not improving. Add psychological therapy she can reach, a practical adherence plan, specific safety netting and a review in about two weeks.
- ●Also acceptable: staying on 50 mg taken daily for a fair four week trial with a dated review; restarting directly at 100 mg (no source gives a rule for restarting after a short gap, and she has already taken 50 mg for eight weeks); switching to another SSRI or an SNRI if she prefers a different tablet once the missed doses are addressed; or, if she still chooses it after the options are explained, a stepwise stop with therapy as the main treatment and an early review.
- ●Not acceptable: stopping abruptly, refusing to discuss stopping, switching or adding drugs before addressing adherence, or leaving without a next step.
Missed Doses and Withdrawal Type Effects
- ●NICE NG222 (1.4.13) says that stopping abruptly, missing doses or not taking a full dose can cause withdrawal symptoms: dizziness, electric shock sensations, irritability, anxiety, low mood and tearfulness, poor sleep, sweating and nausea. The BNF adds that effects may start within 5 days of stopping and are more likely after stopping suddenly following 8 weeks or more of regular use.
- ●Her pattern fits: dizzy, sick, tearful and snappy with head zaps the day after skipped tablets, easing after the next one, and again this morning after three days without. She reads this as the tablet harming her, and that belief is what drives her request to stop.
- ●NG222 (1.4.19) says to reassure people that withdrawal symptoms are not a relapse, are common and may take a few days to settle even after restarting. Where they are troublesome, NG222 (1.4.21) and CKS suggest restarting the original medicine at the previous dose and trying again more slowly.
- ●The issue history is a clue: two issues of 28 tablets but about two weeks still in the box.
Judging Response and Reviewing Contributors
- ●NG222 says that if depression has not responded after 4 weeks of a therapeutic dose, first discuss personal, social and environmental factors, physical and mental health conditions, and adherence. Sertraline 50 mg is a therapeutic dose (BNF maximum 200 mg a day), but her taking of it is not.
- ●Compare with baseline using a validated measure such as the PHQ 9 (0 to 27). NG222 defines more severe depression as 16 or more, so both her scores fall there. Where there is no response, review the diagnosis (NG222 1.9.2 and 1.2.7): past mood elevation (bipolar disorder), previous treatment, sleep, stressful events, alcohol and drugs, and isolation. Bronagh has never been high, drinks modestly and her bloods were normal; her drivers are social.
- ●Ask directly about suicidal thoughts and intent (NG222 1.2.8). She has none, but the question must be asked and the answer recorded.
Increasing Sertraline and Other Options
- ●The BNF dose is 50 mg once daily initially, increased in steps of 50 mg at intervals of at least one week, to a maximum of 200 mg. NG222 (1.9.5) lists the options after limited response, as a shared decision: add group exercise, switch to therapy, increase the dose if tolerated, switch medicine, or combine therapy and medication.
- ●NG222 and CKS warn that higher doses may not work better and can cause more side effects, so review earlier after any rise. A review at about two weeks with a repeat PHQ 9 is a sensible standard (NG222 1.4.11). Warn that nausea, jitteriness, poor sleep or loose stools can return for a week or two, and that benefit is judged over about four weeks of daily dosing.
- ●CKS says a direct switch from sertraline to another SSRI or an SNRI is possible. A switch should come after the missed doses are addressed, or the second tablet will fail for the same reason.
- ●Combinations such as adding mirtazapine or an antipsychotic belong in a specialist setting (NG222 1.9.8 to 1.9.9) and are not a first step. Reassure her that other treatments can be tried if this one fails (NG222 1.9.3).
When She Wants to Stop
- ●NG222 (1.4.12 and 1.4.16) says to explain that stopping usually needs a dose reduction in stages, that most people stop successfully, and to reduce stepwise, for example to half the previous dose and then by smaller proportions as the dose falls, at a pace agreed with the person and waiting until symptoms settle before the next step. The BNF advises reducing sertraline over about 4 weeks or longer, for example 25 mg daily for a week or two, then smaller steps.
- ●Stopping suddenly after 8 weeks carries a higher risk (BNF), and she already knows what withdrawal feels like. NG222 (1.6.1) says people may decline treatment, so a slow stop with therapy as the main treatment and an early review is a legitimate shared decision if she still wants it, provided she understands that depression can return and how to get back in.
Psychological Therapy and Making It Reachable
- ●For a new episode of more severe depression, NG222 ranks combined individual CBT and an antidepressant first, then individual CBT, behavioural activation and others. She responded to telephone CBT before and is willing again, but her referral lapsed after two missed daytime calls.
- ●Anyone aged 18 or over can self refer to NHS Talking Therapies, or the practice can refer. Ask for video, telephone, online or evening appointments and text contact. Treat the lapsed referral as a system failure, not hers.
Adherence and the Quiet Weeks
- ●Missed doses cluster in the weeks Tilly is away, when her morning routine disappears. Anchor the tablet to something fixed, such as the kettle or toothbrush, add a daily phone alarm or a weekly pill organiser, and reorder before supply runs out. NHS advice for a missed dose is to skip it and never double up.
- ●Those weeks are also when her mood is lowest. A plan for them (a fixed morning routine, her Thursday class, Sundays at her mother's) treats the cause of both problems. NG222 lists group exercise as an option after limited response.
Safety Netting, Review, and the Fear of Being Stuck
- ●NG222 (1.2.10 to 1.2.11) says to warn of possible agitation, anxiety and suicidal thoughts when starting or changing treatment, and to ensure people know how to seek help. Be specific: contact the practice the same day if mood drops, agitation grows or withdrawal type symptoms do not settle; when closed, call NHS 111 and select the mental health option; call 999 or go to A&E if she feels she may act on thoughts of ending her life; Samaritans on 116 123 at any time.
- ●NG222 (1.4.11) says treatment might need to continue for at least 6 months after remission, with regular review, and then be tapered. Her fear comes from her mother, who has taken antidepressants for over twenty years. Acknowledge it, ask what her mother's attempts to stop looked like, and explain what is different: she is eight weeks in, treatment is reviewed, it has an end, and tapering is slow and agreed. Do not promise it will never be hard, and never say she will need tablets for life.
Common Mistakes in This Station
- ●Accepting "most days" without asking how many days a week.
- ●Agreeing the tablet has failed and switching or adding a drug before addressing the missed doses.
- ●Telling her to stop straight away, or that she cannot stop, instead of exploring the request and explaining tapering.
- ●Missing that the dizzy, sick, buzzing days are missed dose effects, or explaining them in jargon so she still feels poisoned.
- ●Missing her fear of ending up like her mother, or dismissing it with false reassurance.
- ●Telling her to ring the talking therapies service again with no way round the missed daytime calls.
- ●Not asking directly about suicidal thoughts because she sounds well and copes at work, or giving only vague safety netting.
- ●Leaving without a review date, or booking one more than four weeks away.
- ●Giving no idea how long treatment lasts or how it ends.
Mapped to the RCGP curriculum topic: Mental Health.
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