Woman of 80 On Citalopram Whose Sodium Is Low — Free SCA Practice Case
Woman of 80 on citalopram whose sodium is low
Station Timer
Golden Minute
Initial Introduction
•Introduce yourself
•Ask an open question — "How can I help you today?"
•Listen — don't interrupt
•Catch early cues
Data Gathering
History, ICE & Diagnosis
Clinical Management
Diagnosis, Plan & Decisions
Safety Net
Follow-up & Close
Five cases are free: a live 12-minute consultation with an AI patient each, marked, and no card.
Materials for Candidate
Please review before starting the consultation
Full Name
Doreen Strachan
Age
80 years
Consultation Type
TelephoneAge
80
Situation
Telephone Consultation. You are phoning about a blood result.
Reason for Encounter
"Blood result back this morning. Daughter rang reception yesterday: mother a bit muddled."
Medical Records
- ●PMH: Osteoarthritis. Fall 3 months ago, no fracture. Anxiety since.
- ●Medications: Citalopram 10 mg once daily (8 weeks). Paracetamol PRN.
- ●Allergies: NKDA.
- ●Social: Lives alone. No consent to share information.
Recent Notes
- ●Review, yesterday: GAD 7 13 (16 at start). BP 126/74, pulse 72. Weight 56 kg (59 kg 8 weeks ago).
- ●Bloods, yesterday: Sodium 127, potassium 4.4, urea 4.3, creatinine 66, eGFR 79. FBC, LFTs normal. Sodium 139 ten months ago.
Patient Script
For the friend playing the patient role
Character Overview: You are Doreen Strachan, an 80 year old retired primary school secretary, born in Dundee. You live alone in a bungalow. Your daughter Alison, 52, works part time at a dental practice, lives twenty minutes away, phones a few times a week and calls round on her days off. About three months ago you tripped on the back step and fell. You bruised your hip but nothing was broken and you did not bang your head, but it shook you badly. Since then you have felt jumpy and anxious, afraid of falling again, and you have hardly been out. About eight weeks ago your doctor started you on citalopram for the anxiety. You take one every morning with a glass of water. For two or three weeks you have felt woolly headed and a bit slow, and you think Alison is making a fuss. You have not told anyone how much the forgetfulness frightens you. You are on the landline in the front room, alone, because Alison is at work until four. You are polite, proud and a little embarrassed. Your voice stays light, but slows and goes quiet when you talk about the fall or your sister.
Opening Sentence: "Hello, doctor. Yes, it's Doreen Strachan. The receptionist said you'd be ringing about my blood test. I'm quite all right, you know. It's my daughter who's been making a fuss."
History if Asked (Data Gathering Phase)
- ●What Alison has noticed, and when it started (if asked what has been happening, when it began, or whether it has changed): "Alison says I've been muddled. I think she's overdoing it. I put the milk in the cupboard last week, and my glasses turned up in the fridge, but anyone can do that. And on Sunday I rang her three times in the one morning. I'd forgotten I'd already rung. It started two or three weeks ago, when I'd been on the tablet a month or so, and it's a bit worse than a fortnight ago."
- ●What she was like before, and losing track (if asked for more examples, what she was like before, or whether she knows where she is and who people are): "Sharp as a tack. I did the crossword every morning and kept all the bills straight. Now I walk into a room and wonder what I came for, and I've started writing myself notes. But I always know where I am and who people are." If asked the day or date: "Oh, I'd have to look at the paper. I've been getting the days muddled lately."
- ●Other symptoms (if asked about sickness, headache, falls, dizziness, head injury, blackouts, fits, drowsiness, thirst, diarrhoea or waterworks): "No, none of that. I haven't felt sick or been sick. No headaches, no dizzy spells, and I haven't banged my head. I haven't fallen since the one on the back step, and that was before I started the tablet. I'm wide awake in the day, it's the nights that are the trouble. No more thirsty than usual. No tummy upset, and my waterworks are the same as ever."
- ●The tablet and other medicines (if asked how she takes it, or what else she takes, including from the chemist): "One citalopram every morning, ten milligrams I think. I haven't missed any or doubled up. Otherwise just paracetamol, a couple a week. No water tablets, nothing for my stomach or sleep, no herbal things."
- ●Diet, weight and alcohol (if asked): "Not much, if I'm honest. Tea and toast, mostly, and a bowl of soup at lunchtime. I drink six or seven cups of tea a day, it gives me something to do with my hands. My skirts are loose. A sherry in the evening, two some nights since the fall. I gave up smoking at forty five. No cough or breathlessness."
- ●Mood and nerves (if asked how she has been in herself, how her nerves are, or whether the tablet has helped): "A bit better. The jumpiness has eased off since the tablet, though I still have my moments, mostly at night, lying there going over the fall. I wake in the early hours and that's me awake for the day."
- ●Thoughts of harming herself or not wanting to be here (if asked directly): "No, I would never do anything like that. I wouldn't do that to Alison. I'm not low, I'm just frightened of falling again."
Ideas, Concerns, Expectations
Gating note: Doreen does not raise any of the following herself. Each part comes out only when the doctor asks what she thinks is behind the muddle, what is worrying her, or what she was hoping for from the call.
- ●Ideas: She thinks it is her age and her nerves since the fall. "I've not been myself since I had that fall. And I'm eighty, things start to go."
- ●Concerns: If asked what worries her most, or whether she fears for her memory, her voice goes quiet: "My sister Elspeth, up in Perth. She started just like this, forgetting things, saying the same thing twice. Two years and she was in a home and didn't know me. I think it's started with me." A second fear comes out only when the doctor mentions hospital, admission, or being seen away from home: "I'm not going into hospital. Elspeth went in for a few days after a fall and she never came home again. They'd keep me in and that would be that."
- ●Expectations: "I thought you'd tell me it's my age and my nerves and it'll pass, or give me something for my memory. I never thought it was the blood."
If Asked: Background
Gating note: Doreen answers each of these plainly when the doctor asks about it.
- ●Medical history: "Just my knees, arthritis in both. Otherwise very well. No heart trouble, no sugar, nothing wrong with my kidneys or thyroid that I know of." She turned down talking therapy when it was offered after the fall: "I couldn't face talking to a stranger about it." Allergies: none. Her sister Elspeth, eighty four, has dementia. Nobody else.
- ●Any other symptom she is asked about (weakness, speech, fever, chest pain, constipation, a rash): "No, nothing like that."
- ●Living situation and driving: Alone in a bungalow with no stairs. Alison could be with her within about half an hour if asked. A neighbour, Jean, pops in most mornings but has not been in yet today. She still drives, but only to the shops and the garden centre.
- ●Her day and the fall (if asked how she is managing): "I potter. I've stopped doing the crossword, and I haven't been to my choir since the fall. I hardly go out now, I'm frightened of going over again. I never used to be like this." If asked why she did not say how bad it was: "Alison has her own life. I don't like being a nuisance."
- ●Talking to Alison (if asked): "Of course you can. She's at work until four, but she'll leave if you ring her. Don't frighten her, though."
Responses to Management (The Negotiation Phase)
- ●If the doctor tells her the sodium (salt) is low, or that the citalopram is the likely cause:
- ●Reaction: Puzzled. "Low salt? I never add salt, not for years. Should I be putting more on my food?" She is satisfied if told extra salt is not the answer. "The tablet? It was you that gave it to me. Did I do something wrong?" She settles if told it is a recognised effect at her age and nothing she did caused it. If told the muddle may be due to the sodium: "So it might not be what Elspeth had? Will I get my memory back?" She accepts an honest answer that it usually improves and her memory will be rechecked. If promised it is not dementia: "You can't know that, can you?"
- ●If the doctor says she must be seen today, or mentions hospital or an ambulance:
- ●Reaction: Resists. "Today? Can't it wait until the morning?" About hospital: "Not the hospital. Elspeth went in for a few days after a fall and she never came home." If the doctor acknowledges that first, she calms a little. If the doctor argues without acknowledging it, she digs in: "I'll take my chances at home." She gradually gives way if the doctor explains why it matters, offers to phone ahead, or says Alison can go with her: "Well, if Alison comes with me, and you'll ring them so they know I'm coming?" Offered the surgery first, she is relieved. She accepts an ambulance only if told it is for her safety and Alison cannot come promptly. If told not to drive: "No, I suppose not, with my head like this."
- ●If the doctor suggests repeating the blood test in a few days, or waiting:
- ●Reaction: Agrees too readily. "Oh, that would suit me much better. I'll get Alison to bring me at the end of the week." If told it cannot wait, she asks: "Is it really that serious? What could actually happen?" She wants a straight, proportionate answer. "So it could make me fall, or have a fit, if it dropped lower? But it can be put right?" She is reassured that it usually improves once the cause is dealt with.
- ●If the doctor tells her to stop the citalopram, suggests another antidepressant, or offers support:
- ●Reaction: Worried. "Stop it just like that? My sister got terribly dizzy when she came off hers. And what about my nerves?" She is reassured by a plan for checking on her. Another antidepressant straight away makes her uneasy: "Would that not do the same thing?" Offered talking therapy, she is more open: "I said no before, but maybe. Would somebody ring me, so I'm not left on my own with it?"
- ●If the doctor asks to speak to Alison without asking her first, or asks her to stand, walk or check her pulse:
- ●Reaction: Stiff about Alison: "I'd rather you'd asked." She agrees once asked: "Yes, ring her. She's worried sick already." Asked to do anything physical, she declines: "I'm not walking round the room with the phone to my ear, doctor. If you want to look me over, I can come in."
- ●If the doctor checks the plan, gives safety netting, or mentions follow up:
- ●Reaction: Asked to repeat it, she writes it down: "No more of the tablet. Alison takes me. I take my tablets and the blood result." To "ring us if you feel worse": "What would worse look like? Who do I ring?" About follow up: "When would somebody check on me, then? Would it be you?"
Mark Scheme
Domain 1: Data Gathering and Diagnosis
Domain 2: Clinical Management and Medical Complexity
Domain 3: Relating to Others
Clinical Learning Points
The Core Dilemma and the Model Plan
- ●Mrs Strachan is 80, anxious since a fall three months ago and eight weeks into citalopram 10 mg, with a sodium of 127 mmol/L and a new "bit muddled". The skill is not letting anxiety, age or fear of dementia explain the muddle, grading urgency by symptoms rather than the number, and getting her seen the same day despite her dread of hospital.
- ●Model answer: probable citalopram induced hyponatraemia, symptomatic because of the new confusion. Arrange same day hospital assessment through the on call medical team, stop the citalopram, ensure the cause is investigated, hand over, make the journey safe, and plan her mood, review and safety netting.
- ●Also acceptable: a same day discussion with the on call medical or endocrinology team acted on that day; or an in person review within hours with repeat bloods that day and the admission decision made that day. Not stopping the citalopram until assessed, with the assessing team deciding, also passes. No antidepressant afterwards, with talking therapy for the anxiety, or a later monitored choice such as mirtazapine with a sodium check, both pass.
Grade It by Symptoms as Well as by the Number
- ●By number: mild is 130 to 135 mmol/L, moderate 125 to 129 and severe below 125 (Society for Endocrinology; NICE CKS Hyponatraemia, revised October 2025).
- ●By symptoms: severe means vomiting, seizures or reduced consciousness; moderately severe means nausea without vomiting, confusion or headache. Decisions should follow the symptoms and signs, not the degree of hyponatraemia.
- ●Hers is moderate by number with a new muddle. CKS also lists poor concentration among the features of mild chronic hyponatraemia, so grading is a judgement, but in an 80 year old whose thinking has changed over weeks the safe reading is symptomatic. She has no severe features, which shapes how she travels, not whether she is seen today.
- ●Hers is chronic (48 hours or more), which matters for how fast the sodium may be corrected.
The Disposition Decision: Three Routes
- ●Emergency hospital assessment. CKS advises emergency admission for symptomatic or severe hyponatraemia and when hypovolaemia is suspected. This is the model answer because she is symptomatic, lives alone and needs monitored correction.
- ●Same day specialist discussion or face to face review. A call to the on call medical or endocrinology team, or an examination within hours with repeat bloods that day, is reasonable if the admission decision is made that day. Volume status (pulse, lying and standing blood pressure, signs of dehydration) cannot be judged by telephone.
- ●Remote management with a repeat test. CKS describes this for asymptomatic mild results: repeat the sodium ideally within 24 hours, stop or reduce a contributing medicine and recheck after two weeks. Asymptomatic moderate results are discussed with endocrinology. A repeat in days, or even tomorrow, is not enough for her.
What the Hospital Team Will Do, and Why Not Salt or Fluid Advice
- ●Confirm hypotonic hyponatraemia with serum osmolality (below 275 mOsm/kg), then use urine osmolality, urine sodium and clinical volume status to find the cause. Further tests include glucose, thyroid function and cortisol (CKS).
- ●SIAD (the syndrome of inappropriate antidiuresis) is a diagnosis of exclusion. An SSRI is a recognised cause, but a low solute diet, alcohol, thyroid or adrenal disease, chest disease and malignancy can contribute or mimic it.
- ●Treatment follows the symptoms, and correction is limited to avoid osmotic demyelination: the Society for Endocrinology gives 10 mmol/L in the first 24 hours and 18 mmol/L in 48 hours. That is why correction is monitored and why extra salt or tea changes at home are not the plan. Fluid restriction is part of specialist SIAD treatment, decided once cause and volume status are known, not telephone advice for a symptomatic result.
Stopping the Citalopram
- ●CKS Depression advises that if hyponatraemia is suspected the antidepressant is stopped and the person managed appropriately. CKS Hyponatraemia says to stop or reduce a contributing medicine and repeat the sodium after two weeks.
- ●NICE NG222 (the depression guideline, whose advice on stopping antidepressants is widely applied to other indications such as anxiety) usually asks for gradual reduction but allows more rapid withdrawal for serious side effects, giving hyponatraemia as an example (1.4.16). At 10 mg for eight weeks, the lowest usual older adult dose (maximum 20 mg), stopping is reasonable.
- ●Warn her what to expect. Withdrawal symptoms are usually mild, may start within days and usually settle within one to two weeks, and are not a relapse (NG222 1.4.14, 1.4.19). The BNF notes they are more likely after eight weeks or more.
- ●Record the reaction. STOPP criteria, quoted in the BNF, list SSRIs as potentially inappropriate with a sodium below 130 mmol/L.
Her Anxiety Treatment Afterwards
- ●Do not start another SSRI or an SNRI while the sodium is low. The BNF links hyponatraemia with all antidepressants, more often with SSRIs.
- ●Mirtazapine is a non SSRI alternative but is off label for anxiety and not risk free: the BNF lists hyponatraemia and SIADH (frequency not known), and CKS advises caution in older age. If used, check the sodium soon after starting. No antidepressant at all is also reasonable if her anxiety has settled, and NICE CG113 offers self help and psychological therapy for anxiety before drugs.
- ●Her GAD 7 (generalised anxiety disorder 7 item scale) was 16 at the start and 13 now. Revisit talking therapy, which she declined, once the sodium has recovered, and review whether an antidepressant is still needed.
- ●Ask directly about thoughts of self harm and of not wanting to be here. Doreen has none and her risk is low, but stopping a treatment is a point to keep close contact, not leave a gap. Arrange a named review within about two weeks.
Other Contributors and Other Causes of Confusion
- ●Low solute intake with high water intake lowers sodium, and CKS gives a tea and toast diet as an example. She eats little, drinks six or seven cups of tea a day and has lost weight. Alcohol also contributes and adds to falls risk.
- ●New confusion in an older person has a wide differential (infection, head injury, constipation, medicines, metabolic causes), so ask about falls and head injury.
- ●Do not label her with dementia on the basis of an acute muddle. If the confusion persists after the sodium is corrected, reassess her memory. If the sodium does not recover after the medicine is stopped, look for another cause and refer to endocrinology (CKS).
Explaining It and Handling Her Fears
- ●Use plain words: the tablet can make the body hold on to water and dilute the salt in the blood, it is a recognised effect more likely at her age, and nothing she did caused it. Extra salt is not the treatment, because correction has to be controlled.
- ●Be honest and in proportion: a further fall in sodium could cause falls or fits, but it usually improves once the cause is removed.
- ●Her fear of dementia deserves a straight answer: a low sodium can cause this kind of muddle and it often improves, so her memory will be checked again. Do not promise that it is not dementia.
- ●Acknowledge her fear that going into hospital means not coming home, as happened to Elspeth, before arguing about admission, then offer practical routes: Alison going with her, a call ahead so she is expected, or being seen at the surgery first.
- ●She has capacity. If she still declines, record that she understands the risks, agree the next best same day option and the 999 triggers, and ask whether Alison can stay with her.
- ●Ask her permission before involving Alison, as no consent to share information is recorded.
Safety Netting and Follow Up
- ●Before she is seen she should not drive, should have someone with her, and should call 999 rather than wait for her lift if she becomes very drowsy or hard to wake, is sick, has a fit or blackout, falls or hits her head, becomes much more confused or has a sudden severe headache.
- ●Afterwards: review within about two weeks for mood and safety, repeat the sodium about two weeks after stopping (sooner if the hospital advises), recheck her memory once the sodium is normal, and offer talking therapy for the anxiety.
Common Candidate Mistakes in This Station
- ●Calling the muddle anxiety, age or dementia and repeating the sodium in a few days with no same day assessment.
- ●Treating 127 mmol/L as mild, or judging urgency by the number alone.
- ●Continuing the same dose of citalopram until a repeat result.
- ●Starting sertraline, another SSRI or venlafaxine, or restarting citalopram, while the sodium is still low.
- ●Advising extra salt or less tea as the plan, or accepting her refusal of hospital without another same day route.
- ●Letting her drive or wait alone, and ringing Alison without asking her first.
- ●Not asking about mood, anxiety and self harm in an older woman about to have her antidepressant stopped.
- ●Missing the tea and toast diet and the alcohol, or not asking about falls and head injury.
- ●Promising it is not dementia, or not acknowledging her fear of hospital.
- ●"Ring if you feel worse" with no symptoms and no mention of 999.
Mapped to the RCGP curriculum topic: Metabolic Problems and Endocrinology.
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