Man On Hormone Treatment for Prostate Cancer Told He Has Osteoporosis — Free SCA Practice Case
Man on hormone treatment for prostate cancer told he has osteoporosis
Station Timer
Golden Minute
Initial Introduction
•Introduce yourself
•Ask an open question — "How can I help you today?"
•Listen — don't interrupt
•Catch early cues
Data Gathering
History, ICE & Diagnosis
Clinical Management
Diagnosis, Plan & Decisions
Safety Net
Follow-up & Close
Five cases are free: a live 12-minute consultation with an AI patient each, marked, and no card.
Materials for Candidate
Please review before starting the consultation
Full Name
Cedric Lamptey
Age
70 years
Consultation Type
TelephoneAge
70
Situation
Telephone Consultation. Booked to discuss a bone scan result.
Reason for Encounter
"I've had a letter about my bone scan and it says to speak to my GP."
Medical Records
- ●PMH: Prostate adenocarcinoma, radical radiotherapy completed 21 months ago. Hypertension. Reflux.
- ●Medications: Goserelin 10.8 mg implant every 12 weeks (started 2 years ago), amlodipine 5 mg OD, lansoprazole 15 mg OD.
- ●Allergies: NKDA.
- ●Social: Retired tax inspector.
Recent Results
- ●DEXA (requested by oncology): lumbar spine L1 to L4 T score minus 2.8, total hip minus 2.3, femoral neck minus 2.6.
- ●eGFR (oncology bloods, 3 months ago): 71.
Patient Script
For the friend playing the patient role
Character Overview: You are Cedric Lamptey, a 70 year old retired tax inspector. You live with your wife Hortense in a semi detached house, and your son Kofi lives in Leeds with his two young children, whom you visit most months. You were diagnosed with prostate cancer about two years ago, had a course of radiotherapy, and have had a hormone injection implant every twelve weeks since, which the nurse here gives you. Your last cancer results were good and the plan is to carry on until you have had three years in total. The hospital arranged a bone scan because of the injections and sent you a letter saying the result was low and you should see your GP. You are a precise, courteous man who likes things explained properly and writes things down. You are surprised and a little unsettled, because you always assumed brittle bones was something that happened to older women. Your voice is polite and measured, with a worried edge when you mention your mother or the injections.
Opening Sentence: "Good morning, doctor. I've had a letter from the hospital about my bone scan and it says my bones have come out low and that I should speak to my GP. I have to say, I'm rather surprised, I thought that sort of thing was for women."
History if Asked (Data Gathering Phase)
- ●Why the scan was done: "The cancer doctors said the injections can thin the bones, so they sent me for a scan to check. I didn't think much of it until the letter came."
- ●The cancer treatment: "Radiotherapy finished about twenty one months ago. I've had the implant every twelve weeks since, the nurse here gives it. I'm told the PSA is undetectable. They want me to carry on for a year more, to three years altogether."
- ●Symptoms from the treatment: "Hot flushes, mostly in the evening. I'm tired a lot of the time. I've put on about a stone. My drive for anything, well, that has gone, and I'd rather not go into it."
- ●Fractures: "None. I've never broken a bone in my life."
- ●Falls: "No falls. I tripped on a kerb once last year but I caught myself on a lamp post."
- ●Back pain and height: "No back pain. I don't think I've got shorter, though Hortense says I look a bit rounder in the shoulders than I used to."
- ●Bone pain or other symptoms: "No bone pain anywhere. No weight loss, my appetite is normal, no fevers and no infections."
- ●Family: "My mother broke her hip at 82 when she slipped in the kitchen. She never really walked properly again and died within two years. My father had nothing like that."
- ●Smoking and alcohol: "I gave up smoking about twelve years ago. I smoked about fifteen a day for thirty years. I have a pint, sometimes two, most evenings with my tea. Perhaps ten to fourteen units a week if I'm honest."
- ●Diet and sunlight: "I don't like milk. I have a yoghurt now and then, a bit of cheese, and I eat fish. I get outside a fair amount in the garden, but I don't take any vitamins."
- ●Activity: "I used to walk five miles. Now I manage about twenty minutes, to the shops and back. I've never done anything with weights."
Ideas, Concerns, Expectations
Gating note: Cedric does not raise any of the following himself. Each part comes out only when the doctor asks what he makes of the result, what is worrying him, or what he is hoping for.
- ●Ideas: He believes brittle bones is something that happens to women after the menopause. He wonders whether the injections have caused it, or whether he is simply old. "I thought that was a women's complaint. Is it the injections? Or is it just age?"
- ●Concerns: His first fear is that the doctors will stop the injections and the cancer will come back. His second is ending up like his mother, who never recovered from her broken hip. His third is that his friend Ambrose told him that Ambrose's wife took bone tablets and "ended up with a rotten jaw". "I'm not stopping the injections, am I? I don't want the cancer back. And Ambrose's wife had a terrible time with her jaw after those tablets."
- ●Expectations: He wants to be told what the result means in plain terms, whether the cancer treatment carries on, and what can be done. He would prefer to avoid anything that means more hospital trips. "I'd like to know where I stand, and what you'd advise. I just don't want to lose my place in the cancer plan."
If Asked: Medical History and Medications
Gating note: Cedric answers each of these plainly when the doctor asks about it.
- ●Other health problems: "Blood pressure, tablets for that, and acid reflux. Nothing else. No diabetes, no thyroid trouble, no liver or kidney problems that I know of."
- ●Steroids and other tablets: "No steroid tablets or inhalers, ever. Only the amlodipine and the lansoprazole, which I've had for about six years."
- ●Reflux and swallowing: "I get heartburn now and then after spicy food, and the lansoprazole keeps it under control. I've never had trouble swallowing, never had an ulcer or a camera test, and I can sit up as long as I like."
- ●Bowels and stomach: "Normal. No diarrhoea, no coeliac, nothing like that."
- ●Teeth: "I haven't seen the dentist for about eighteen months. A lower back tooth is a bit wobbly and I've been putting it off. No dentures, otherwise my teeth are good."
- ●Mood: "A bit flat some days with the tiredness, but I'm not depressed."
- ●Allergies: "None."
Social History and Lifestyle Impact
- ●Home and family: Cedric lives with Hortense, who still works two days a week as a school secretary. He is close to Kofi's children and likes lifting his four year old grandson, which he now wonders about.
- ●Daily life: Retired for five years. He is on the committee of the local history society and drives to its meetings. He is happy to book appointments any weekday.
- ●Alcohol and exercise: If the doctor suggests cutting down, he thinks a pint with his tea is harmless but is willing to hear why. He is reluctant about gym work but would do walking or home exercises he could write down.
- ●Practicalities: He wakes early and has a cup of tea first thing. He is happy to change that habit if it is explained.
If Asked: Associated Symptoms
Gating note: Cedric answers these only when asked. Every one is negative unless stated.
- ●If asked about new back pain, pain in the ribs or hips, or a recent fall: "No, none at all."
- ●If asked about thirst, passing a lot of water, constipation or kidney stones: "No."
- ●If asked about night sweats, fevers or recurrent infections: "Only the flushes, which are the injections. Nothing else."
- ●If asked about weight loss: "No, the opposite. I'm heavier."
- ●If asked about testing his own balance, standing on one leg or checking his height: "I'd rather not try that on the phone. Can you check me in the surgery?"
- ●If asked about bone pain, muscle weakness or trouble getting up from a chair: "No."
Responses to Management (The Negotiation Phase)
- ●If the doctor explains what the result means and why it has happened:
- ●Reaction: Interested and a little reassured to have an explanation. "So men get it as well, especially on these injections? Why did nobody mention that when I started?" He asks for it to be put simply. "So it's the treatment lowering my hormones that is thinning my bones? Right, I understand that." He asks, "Should I be worried I'll break something?" If told it is a raised risk and not a certainty: "Right, so it is a risk rather than a certainty."
- ●If the doctor discusses stopping, changing or continuing the injections, or involving the cancer team:
- ●Reaction: Anxious and then relieved. "I don't want it stopped unless the cancer team agree." If told the injections carry on and the cancer team will be told: "Good, that's what I wanted to hear. Will you write to them?" If told that stopping is something only the cancer team would discuss: "Then I'll leave that with them."
- ●If the doctor suggests tests before treatment:
- ●Reaction: Agreeable but wants the reason. "What are the blood tests looking for?" He agrees to bloods and to being seen in the surgery. "I'm happy to come in. I haven't had my bloods done since the hospital three months ago."
- ●If the doctor suggests a bone strengthening tablet:
- ●Reaction: Cautious, asks practical questions. "How do I take it? I have my tea first thing." "I already have heartburn and take lansoprazole, will it make that worse?" "How long would I be on it?" Then, if the jaw is not mentioned: "Ambrose said his wife's jaw went rotten. Is that a risk?" He accepts a dental check and a tooth plan. "I'll book the dentist this week. Can I do that before I start?" If a yearly injection or a different treatment is offered instead: "I'd rather tablets if they are as good, but I'll listen."
- ●If the doctor advises on calcium, vitamin D, alcohol and exercise:
- ●Reaction: Pragmatic. "I don't drink milk. Can I get it from tablets?" About alcohol: "A pint with my tea. Is that really a problem?" He accepts a sensible limit if the reason is given. About exercise: "Weights at my age? I could do a walking plan, if you write it down. Is lifting my grandson all right?"
- ●If the doctor gives outlook, follow up or safety netting:
- ●Reaction: Wants specifics. "Will this ever go back to normal? How will I know it's working?" If safety netting is vague, such as "come back if you have problems": "What sort of problems? I'd like it written down." He repeats back clearly when given specific symptoms and what to do.
Mark Scheme
Domain 1: Data Gathering and Diagnosis
Domain 2: Clinical Management and Medical Complexity
Domain 3: Relating to Others
Clinical Learning Points
The Core Dilemma and the Model Plan
- ●Cedric is a 70 year old man with prostate cancer on a goserelin implant every 12 weeks for two years. His oncology bone scan shows osteoporosis (lumbar spine T score minus 2.8, femoral neck minus 2.6). He believes this is a women's problem, fears the cancer injections will be stopped, and has heard a story about "rotten jaws" from bone tablets. The station tests whether the candidate recognises androgen deprivation therapy (ADT) as the main cause, protects his cancer treatment, treats the bones safely and counsels well.
- ●The model plan has six parts. Explore what he understands. Explain that hormone treatment is the main reason and that his mother's hip fracture adds risk. Keep the injections going and tell the oncology team. Check calcium, vitamin D, kidney function and other secondary causes, and see him in person. Offer an oral bisphosphonate after checking reflux, swallowing, calcium and teeth. Give a dental plan, calcium and vitamin D, lifestyle advice, follow up and specific safety netting.
- ●Acceptable alternatives: starting the tablet after the bloods return or at a face to face review the same week; agreeing that the oncology or an osteoporosis service starts treatment, provided the GP makes sure someone owns it; using FRAX or QFracture or deciding directly from the T score; an intravenous or injectable agent through a specialist if an oral tablet is unsuitable or he prefers it; ibandronate if first line tablets are not tolerated.
Why Men on ADT Lose Bone
- ●ADT suppresses testosterone and, through it, oestrogen, which both restrain bone breakdown. Bone loss is fastest in the first year and continues while treatment lasts. Hot flushes, tiredness, weight gain and loss of libido are other effects, and he mentioned all of them.
- ●Men also get osteoporosis, usually later than women. Fragility fractures in men carry a higher death rate than in women, so the message that "this is a women's complaint" needs gentle correction.
- ●Osteoporosis is silent until a fracture occurs. He has no back pain, height loss or falls, which is reassuring but does not remove the risk. A candidate who asks about all three is excluding a vertebral fracture as far as a telephone call allows.
Other Contributors to Look For
- ●Risk factors in the history: his mother's hip fracture at 82, past smoking (15 a day for 30 years, stopped 12 years ago), alcohol of roughly 10 to 14 units a week, a low dairy intake, reduced activity since treatment, and long term proton pump inhibitor use (lansoprazole for about six years), which is a recognised, modest contributor.
- ●Secondary causes to exclude by history and tests: diabetes, thyroid disease, hyperparathyroidism, coeliac disease or malabsorption, liver or kidney disease, myeloma, vitamin D deficiency and steroid exposure. He has none by history. Reasonable bloods are bone profile with calcium and albumin, vitamin D, kidney function, full blood count, inflammatory markers, thyroid function, liver function and a myeloma screen as the GP judges appropriate. His eGFR three months ago was 71.
- ●The aim is to correct low calcium or vitamin D before starting a bisphosphonate, because hypocalcaemia is a contraindication to alendronic acid in the BNF and low vitamin D must be corrected first.
Keep the Cancer Treatment; Involve Oncology
- ●The cancer takes priority. A GP does not stop, delay or switch ADT because of a bone result. Any change to cancer treatment belongs to the oncology or urology team.
- ●Tell the cancer team the result, say who will start and monitor bone treatment, and document it. Many oncology units have their own bone health pathway, so a call or letter to confirm who prescribes avoids duplication or a gap. Giving Cedric a clear answer on this addresses his main fear.
Deciding to Treat
- ●NICE CKS (Osteoporosis, prevention of fragility fractures) advises offering an oral bisphosphonate to men over 50 with osteoporosis confirmed on DXA (T score of minus 2.5 or less) when there are no contraindications and after counselling. Cedric meets that threshold at the spine and femoral neck, and ADT adds weight. Watching and repeating the scan is not enough.
- ●CKS offers alendronate 70 mg weekly or risedronate 35 mg weekly first line, with ibandronate if those are unsuitable. It notes that only risedronate is licensed in men (the BNF lists alendronic acid for men as 10 mg daily), so a candidate may reasonably choose either and should know the licence position. If oral bisphosphonates are not tolerated or contraindicated, CKS advises specialist referral, where zoledronic acid, denosumab and other agents are options.
- ●NICE NG259 (Osteoporosis: risk assessment, July 2026, replacing CG146) lists ADT as a factor that raises fracture risk beyond what FRAX or QFracture capture, and advises considering drug treatment, as a shared decision, for people aged 50 and over with a T score of minus 2.5 or less. Its treatment chapters are still to come, so CKS remains the source for drug choice. NICE NG131 (prostate cancer) gives no bone protection advice. FRAX or QFracture can support the decision but are not required here.
Is an Oral Bisphosphonate Safe for Him?
- ●Check the things that make oral bisphosphonates unsafe: oesophageal abnormality, stricture or achalasia, inability to stay upright for 30 minutes, hypocalcaemia and significant renal impairment. The BNF advises avoiding alendronic acid if creatinine clearance is below 35 mL/minute. His eGFR is 71.
- ●Controlled reflux on a proton pump inhibitor is not a contraindication. It deserves a question and a warning to stop and seek help if new pain on swallowing, chest pain or worsening heartburn develops.
- ●Counsel on technique, in line with the BNF: take with plenty of plain water, sitting or standing, on an empty stomach at least 30 minutes before breakfast or other medicines, and stay upright for at least 30 minutes. Cedric has tea on waking, so agree a routine and a fixed day of the week.
Dental Health and the Rare Risks
- ●The BNF says all patients with cancer and patients with poor dental status should have a dental check, with any necessary remedial work, before bisphosphonate treatment or as soon as possible after starting. Cedric has a wobbly tooth and has missed 18 months of check ups. Advise booking now, telling the dentist about the medicine, and keeping good oral hygiene.
- ●Osteonecrosis of the jaw is rare with oral bisphosphonates in osteoporosis, and the risk is substantially greater with intravenous bisphosphonates for cancer. That distinction answers the friend's story honestly. Atypical femoral fracture is also rare: report new thigh, hip or groin pain, stop the tablet and arrange femur imaging as CKS advises.
- ●Neither risk should be exaggerated or denied. A man who hears a fair account is more likely to take a drug that cuts his fracture risk.
Calcium, Vitamin D, Alcohol and Activity
- ●CKS advises that if calcium intake is adequate (700 mg a day), vitamin D of 400 international units daily should be prescribed for people with little sun exposure. If intake is inadequate, calcium with vitamin D is advised. Cedric dislikes milk and has little dairy, so a supplement or a diet plan is appropriate once his calcium and vitamin D levels are known.
- ●Alcohol above recommended limits is a risk factor. Explain this without a lecture and agree to a realistic limit.
- ●Weight bearing and strength exercise help bone and muscle, and falls prevention matters. A written walking plan fits him. Lifting his grandson is reasonable and there is no need to ban it.
Follow Up and Safety Netting
- ●Check early on how he is tolerating it, review adherence at about 12 months as CKS advises, and explain that treatment is long term with periodic review of fracture risk. CKS describes continuing for several years before reassessing, so "for life" and "a few weeks" are both wrong.
- ●Safety net by symptom with an action: new back pain or loss of height (see within days); thigh, hip or groin pain (stop and be seen); painful swallowing, chest pain or new heartburn (stop and call); jaw pain, swelling or a loose tooth (dentist and GP). Cedric likes written instructions, so offer them.
Common Mistakes in This Station
- ●Telling him it is just age, or ignoring that ADT is the main driver.
- ●Advising a stop or delay of the goserelin, or leaving oncology unaware.
- ●Offering only calcium, vitamin D and exercise for confirmed osteoporosis.
- ●Starting a tablet without checking calcium and vitamin D, reflux, swallowing, kidney function and teeth.
- ●Giving no dosing instructions, or letting him take it with his morning tea.
- ●Dismissing the jaw story, or presenting jaw damage and thigh fractures as likely.
- ●Lecturing about alcohol or banning lifting and exercise.
- ●Vague safety netting such as "come back if worried" and no check of understanding.
Mapped to the RCGP curriculum topic: Older Adults.
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